Mariko okada biography template

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    • Okada Mariko

    岡田　眞里子

    Institute for Protein Research, Professor

    keyword BioDX，Bioinformatics，inflammation，immunology，cancer，mathematical modeling，omics，transcriptional regulation，signal transduction，Systems Biology

    Education

    • - 1988/03, Tokyo University of Agriculture and Technology

    Research History

    • 2024/10 - Present, Imperial College London, Department of Bioengineering, Provost’s Visiting Professor of Systems Biology (クロアポ）
    • 2016/07 - Present, Osaka University, Institute for Protein Research, Professor
    • 2022/12 - 2024/03, Osaka University, WPI Premium Research Institute for Human Metaverse Medicine (WPI-PRIMe), Deputy Director, PI
    • 2022/04 - 2024/03, Osaka University, Institute for Protein Research, Director
    • 2013 - 2016/06, RIKEN, IMS, Team leader
    • 2009 - 2013, RIKEN, RCAI, Team leader
    • 2008 - 2009, RIKEN, ASI
    • 2000/07 - 2008/07, RIKEN, GSC, Researcher, Senior Researcher, Team leader
    • 1996 - 1999, University of California, Davis, Visiting Scientist
    • 1988 - 1996, Novo Nordisk Bioindustry, R&D, Researcher, Group leader, Manager

    Research Areas

    • Life sciences, Applied biochemistry, Life Sciences
    • Life sciences, Cell biology, Systems Biology

    Professional Memberships

    • 日本生化学会
    • 日本免疫学会
    • International Society of Systems Biology (ISSB) (Committee Member)
    • JAPANESE SOCIETY FOR BIOINFORMATICS
    • THE BIOPHYSICAL SOCIETY OF JAPAN
    • THE JAPANESE CANCER ASSOCIATION
    • THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

    Papers

    • Predicting Drug-Gene Relations via Analogy Tasks with Word Embeddings, Hiroaki Yamagiwa,Ryoma Hashimoto,Kiwamu Arakane,Ken Murakami,Shou Soeda,Momose Oyama,Yihua Zhu,Mariko Okada,Hidetoshi Shimodaira, arXiv, arXiv, 2024/12
    • An attention-based deep neural network model to detect cis-regulatory elements at the single-cell level from multi-omics data, Ken Murakami,Keita Iida,Mariko Okada, Cold Spring Harbor Laboratory, 2024/10/22
    • DynProfiler: A Python package for comprehensive analysis and interpretation of sig
      Mariko okada biography template

    Following a PhD in the Laboratory of Molecular Biology at Ghent University (Belgium), I carried out Postdoctoral studies at the Ludwig Institute for Cancer Research, London, where I was involved in a systematic effort to isolate the genes encoding PI 3-kinases (PI3Ks).

    In my independent laboratory, we developed a unique genetic approach to create an unparalleled series of mouse models that allowed us to uncover the roles of multiple PI3K family members in biology, and to faithfully predict organismal PI3K inhibitor activity.

    We discovered PI3Kdelta which we took from gene cloning and preclinical modelling to the generation of PI3Kdelta inhibitors, and the development of clinical strategies to inhibit this PI3K isoform. These studies underpinned the approval of PI3Kdelta-inhibitors for leukaemia and their emerging use in solid tumour immunotherapy.

    Our current research is focused on exploring alternative ways to modulate the PI3K pathway, including in cancer immunotherapy, cancer prevention, and the generation of small molecule PI3K activators.

    B.V. is an elected member of EMBO (European Molecular Biology Organisation) and of the UK Academy of Medical Sciences

    Professor Mariko Okada’s laboratory focuses on dynamics of molecules and genes in cells and analyzes them by combining wet lab experiments and mathematical models, thereby clarifying the quantitative relationship between signalling dynamics, transcriptional regulation, and cell fate.

    Professor Mariko Okada is the Director of the Institute for Protein Research, Osaka University.

    Prof Paolo Salomoni first independent position was in 2003 as Programme Leader Track at the MRC Unit in Leicester, where he was promoted to tenured Senior Group Leader in 2009. Subsequently, he joined the UCL Cancer Institute as Professorial Research Associate and Lead of the Samantha Dickson Brain Cancer Unit. He became UCL Professor of Nervous System Tumour Research in 2015. 

    Since 2017, Paolo Salomoni is hea

  • Education. - 1988/03, Tokyo University of
  • Professor Mariko Okada is

    • .